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A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multiple Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Effects of BMS-986036 in Obese Adults With Type-2 Diabetes

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Trial Profile

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multiple Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Effects of BMS-986036 in Obese Adults With Type-2 Diabetes

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Pegbelfermin (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 06 Dec 2018 Results assessing pegbelfermin (BMS-986036), recombinant PEGylated human fibroblast growth factor 21 (FGF21), in patients with obesity and T2DM predisposed to fatty liver, published in the Obesity (Silver Spring, Md.).
  • 14 Apr 2018 Results of a population pharmacokinetics and exposure-response analysis from NCT02097277, NCT02413372 and one more study, presented at The International Liver Congress 2018.
  • 14 Apr 2018 Results of an integrated safety analysis from NCT02097277 and NCT02413372 studies, presented at The International Liver Congress 2018.

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