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Single center, double-blind, randomized, placebo-controlled, two-period/two-treatment crossover, proof-of-mechanism study investigating the effect of miglustat on the nasal potential difference in adult patients with cystic fibrosis homozygous for the F508del mutation

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Single center, double-blind, randomized, placebo-controlled, two-period/two-treatment crossover, proof-of-mechanism study investigating the effect of miglustat on the nasal potential difference in adult patients with cystic fibrosis homozygous for the F508del mutation

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Miglustat (Primary)
  • Indications Cystic fibrosis
  • Focus Pharmacodynamics; Proof of concept
  • Acronyms MIGLUSTAT-CF

    • Most Recent Events

    • 16 Mar 2018 Status changed from recruiting to completed.
    • 31 Jul 2016 Planned End Date changed from 1 Aug 2017 to 1 Jan 2018.
    • 31 Jul 2016 Planned primary completion date changed from 1 Mar 2017 to 1 Sep 2017.

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