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A Two-Part, Phase I Study of Orally Administered GRC 27864, a Novel, Microsomal Prostaglandin E Synthase-1 Enzyme (mPGES-1) Inhibitor, to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses in Healthy Subjects (Part 1), and of Multiple Doses in Elderly Subjects (Part 2)

Trial Profile

A Two-Part, Phase I Study of Orally Administered GRC 27864, a Novel, Microsomal Prostaglandin E Synthase-1 Enzyme (mPGES-1) Inhibitor, to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses in Healthy Subjects (Part 1), and of Multiple Doses in Elderly Subjects (Part 2)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Zaloglanstat (Primary)
  • Indications Inflammation; Osteoarthritis; Pain; Rheumatoid arthritis
  • Focus Adverse reactions; First in man
  • Sponsors Glenmark Pharmaceuticals Ltd
  • Most Recent Events

    • 16 Sep 2018 Results presented at the 17th World Congress on Pain
    • 16 Oct 2015 Status changed from recruiting to completed, according to ClinicalTrials.gov record.
    • 11 Aug 2015 Planned End Date changed from 1 Jul 2015 to 1 Sep 2015 according to ClinicalTrials.gov record.
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