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A Phase2, Multi-Center, Multi-national, Randomized, Double-blind, Placebo-controlled Parallel-group Clinical Trial to Evaluate the Efficacy and Safety of RPC4046 in Adult Subjects With Eosinophilic Esophagitis

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Trial Profile

A Phase2, Multi-Center, Multi-national, Randomized, Double-blind, Placebo-controlled Parallel-group Clinical Trial to Evaluate the Efficacy and Safety of RPC4046 in Adult Subjects With Eosinophilic Esophagitis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Feb 2019

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At a glance

  • Drugs Cendakimab (Primary) ; Cendakimab (Primary)
  • Indications Eosinophilic oesophagitis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms HEROES
  • Sponsors Celgene Corporation; Receptos

    • Most Recent Events

    • 25 Feb 2019 Results of an exploratory substudy assessing the effect of RPC4046 on Epithelial-Mesenchymal Transition in adults with active eosinophilic esophagitis, presented at the 2019 Annual Meeting of the American Academy of Allergy, Asthma and Immunology
    • 25 Feb 2019 Results from open-label extension phase of this study presented at the 2019 Annual Meeting of the American Academy of Allergy, Asthma and Immunology.
    • 25 Feb 2019 Results of a post-hoc analysis assessing RPC4046 in steroid-refractory subjects, presented at the 2019 Annual Meeting of the American Academy of Allergy, Asthma and Immunology
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