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An Open Label, Randomized Phase 3 Clinical Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Platinum-refractory Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Trial Profile

An Open Label, Randomized Phase 3 Clinical Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Platinum-refractory Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 15 Jul 2022

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At a glance

  • Drugs Nivolumab (Primary) ; Cetuximab; Docetaxel; Methotrexate
  • Indications Carcinoma; Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Pharyngeal neoplasms; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms CheckMate 141
  • Sponsors Bristol-Myers Squibb; Ono Pharmaceutical
  • Most Recent Events

    • 14 Jul 2022 Status changed from discontinued to completed.
    • 04 Dec 2021 This trial has been completed in France (Global end date: 10 Sep 2021).
    • 28 Nov 2021 This trial has been completed in Netherland (End Date: 02 Sep 2021), according to European Clinical Trials Database record.
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