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Phase 2 Proof-of-Activity Study of Oral Posaconazole in the Treatment of Asymptomatic Chronic Chagas Disease (Phase 2, Protocol No. P05267)

Trial Profile

Phase 2 Proof-of-Activity Study of Oral Posaconazole in the Treatment of Asymptomatic Chronic Chagas Disease (Phase 2, Protocol No. P05267)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 May 2017

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At a glance

  • Drugs Posaconazole (Primary) ; Benznidazole
  • Indications Chagas disease
  • Focus Therapeutic Use
  • Acronyms STOP CHAGAS
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 28 Feb 2017 Primary endpoint (Percentage of Participants With a Successful Response as Measured by Qualitative Polymerase Chain Reaction) has not been met, according to results published in the Journal of the American College of Cardiology.
    • 28 Feb 2017 Results published in the Journal of the American College of Cardiology
    • 28 Jan 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
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