Trial Profile

A Multi-center, Open-Label Extension Study of HGT-1111 (Recombinant Human Arylsulfatase A or rhASA) Treatment in Patients With Late Infantile Metachromatic Leukodystrophy (MLD) [EXTENSION OF 700219152]

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 30 Apr 2022

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At a glance

26 Apr 2022 Using data from 3 studies (NCT00418561; NCT00633139; NCT00681811) were used to evaluate the toxic effects of sulfatide and lysosulfatide on the central (CNS) and peripheral (PNS) nervous systems in children with metachromatic leukodystrophy (MLD) and to explore the impact of treatment with intravenous recombinant human arylsulfatase A (rhASA) on myelin turnover, presented at the 74th Annual Meeting of the American Academy of Neurology 2022.
07 May 2014 New trial record

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