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Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

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Trial Profile

Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 May 2020

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At a glance

  • Drugs Linaclotide (Primary)
  • Indications Irritable bowel syndrome
  • Focus Pharmacodynamics

    • Most Recent Events

    • 13 May 2020 Primary endpoint (Change from Baseline in Prolongation and normalization of rectal MEP and anal MEP at 10 weeks.) has been met, as per Results published in the Alimentary Pharmacology and Therapeutics
    • 13 May 2020 Primary endpoint (Change from baseline in Prolongation and normalization of anal CEP and rectal CEP responses at 10 weeks.) has been met, as per Results published in the Alimentary Pharmacology and Therapeutics
    • 13 May 2020 Results published in the Alimentary Pharmacology and Therapeutics

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