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A Phase Ib/II Trial Evaluating the Efficacy of MK-3475 and Trastuzumab in Patients With Trastuzumab-resistant, HER2-positive Metastatic Breast Cancers

Trial Profile

A Phase Ib/II Trial Evaluating the Efficacy of MK-3475 and Trastuzumab in Patients With Trastuzumab-resistant, HER2-positive Metastatic Breast Cancers

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 19 Aug 2022

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At a glance

  • Drugs Pembrolizumab (Primary) ; Trastuzumab
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms KEYNOTE-014; PANACEA

Most Recent Events

  • 11 Feb 2019 Results (Data cut-off: Aug 7, 2017) published in the Lancet Oncology
  • 27 Sep 2018 Status changed from active, no longer recruiting to completed.
  • 27 Jun 2018 This trial has been completed in Austria (End date: 2018-01-31), according to European Clinical Trials Database.

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