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A Translational Companion Protocol to GOG229O: A Randomized Phase II Study With a Safety Lead-In to Assess the Antitumor Efficacy of the MEK Inhibitor Trametinib Alone or in Combination With GSK2141795, an AKT Inhibitor, in Patients With Recurrent or Persistent Endometrial Cancer

Trial Profile

A Translational Companion Protocol to GOG229O: A Randomized Phase II Study With a Safety Lead-In to Assess the Antitumor Efficacy of the MEK Inhibitor Trametinib Alone or in Combination With GSK2141795, an AKT Inhibitor, in Patients With Recurrent or Persistent Endometrial Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Trametinib (Primary) ; Uprosertib (Primary)
  • Indications Adenocarcinoma; Endometrial cancer
  • Focus Biomarker; Pharmacodynamics

Most Recent Events

  • 24 Jan 2020 Status changed from active, no longer recruiting to completed.
  • 06 Jan 2020 Planned End Date changed from 31 Aug 2019 to 30 Jan 2020.
  • 06 Jan 2020 Planned primary completion date changed from 31 Aug 2019 to 30 Jan 2020.

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