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A Phase 2 Open-Label Study of the Efficacy and Safety of ABT-199 (GDC-0199) in Chronic Lymphocytic Leukemia (CLL) Subjects With Relapse or Refractory to B-Cell Receptor Signaling Pathway Inhibitor Therapy

Trial Profile

A Phase 2 Open-Label Study of the Efficacy and Safety of ABT-199 (GDC-0199) in Chronic Lymphocytic Leukemia (CLL) Subjects With Relapse or Refractory to B-Cell Receptor Signaling Pathway Inhibitor Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Jul 2023

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At a glance

  • Drugs Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Sponsors AbbVie

Most Recent Events

  • 15 Jun 2023 Results of an analysis assessing matching-adjusted indirect comparison (MAIC) of Pirtobrutinib vs Venetoclax continuous monotherapy from two clinical trials: NCT03740529 and NCT02141282 presented at the 28th Congress of the European Haematology Association
  • 29 Dec 2021 Status changed from active, no longer recruiting to completed.
  • 08 Dec 2020 Results (n=1138) of a retrospective analysis assessing rates of tumor lysis syndrome and outcomes and data were pooled from eight clinical studies: M15-550, M15-889, CLL14, M16-778, M14-032, M13-982, M14-728 and MURANO presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology

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