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A PHASE II, MULTICENTER, RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE EFFICACY AND SAFETY OF RO5520985 PLUS FOLFOX VERSUS BEVACIZUMAB PLUS FOLFOX IN PATIENTS WITH PREVIOUSLY UNTREATED METASTATIC COLORECTAL CANCER

Trial Profile

A PHASE II, MULTICENTER, RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE EFFICACY AND SAFETY OF RO5520985 PLUS FOLFOX VERSUS BEVACIZUMAB PLUS FOLFOX IN PATIENTS WITH PREVIOUSLY UNTREATED METASTATIC COLORECTAL CANCER

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Apr 2019

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At a glance

  • Drugs Vanucizumab (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms McCAVE
  • Sponsors Roche
  • Most Recent Events

    • 02 Jun 2017 Primary endpoint (Progression-free Survival (PFS) as Assessed Using Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1)) has not been met as per the results published at the 53rd Annual Meeting of the American Society of Clinical Oncology.
    • 02 Jun 2017 Final results(n=189) presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
    • 25 Apr 2017 Status changed from active, no longer recruiting to completed.
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