Trial Profile

A Multi-arm, Phase Ib, Open-Label, Multicentre Study to Assess the Safety,Tolerability, Pharmacokinetics and Preliminary Anti-tumour Activity of AZD9291 in Combination With Ascending Doses of Novel Therapeutics in Patients With EGFRm+ Advanced NSCLC Who Have Progressed Following Therapy With an EGFR TKI (TATTON)

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 12 Apr 2025

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At a glance

Drugs Durvalumab (Primary) ; Osimertinib (Primary) ; Savolitinib (Primary) ; Selumetinib (Primary)
Indications Adenocarcinoma; Non-small cell lung cancer; Solid tumours
Focus Adverse reactions; Proof of concept
Acronyms TATTON
Sponsors AstraZeneca

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