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Safety and IOP-Lowering Efficacy of Brinzolamide 10 mg/mL/Brimonidine 2 mg/mL Fixed Combination Eye Drops, Suspension Compared to Brinzolamide 10 mg/mL Eye Drops, Suspension and Brimonidine 2 mg/mL Eye Drops, Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

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Trial Profile

Safety and IOP-Lowering Efficacy of Brinzolamide 10 mg/mL/Brimonidine 2 mg/mL Fixed Combination Eye Drops, Suspension Compared to Brinzolamide 10 mg/mL Eye Drops, Suspension and Brimonidine 2 mg/mL Eye Drops, Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 09 Feb 2023

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At a glance

  • Drugs Brimonidine/brinzolamide (Primary) ; Brimonidine; Brinzolamide
  • Indications Ocular hypertension; Open-angle glaucoma
  • Focus Registrational; Therapeutic Use
  • Sponsors Alcon

    • Most Recent Events

    • 28 Jul 2014 Brinzolamide/brimonidine [Simbrinza] has been approved in the EU based on data from this trial and another pivotal phase III trial, according to a Novartis media release.
    • 28 May 2014 New source identified and integrated, European Clinical Trials Database record (EudraCT2010-024512-34).
    • 28 May 2014 New trial record

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