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A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose, Safety, Pharmacokinetic, and Pharmacodynamic Study of Orally Administered AG-348 in Healthy Volunteers

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Trial Profile

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose, Safety, Pharmacokinetic, and Pharmacodynamic Study of Orally Administered AG-348 in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Mitapivat (Primary)
  • Indications Haemolytic anaemia
  • Focus Adverse reactions
  • Acronyms AG-348MAD; MAD
  • Sponsors Agios Pharmaceuticals

    • Most Recent Events

    • 06 Dec 2016 Results of analysis of whole blood metabolism from two studies ( MAD and DRIVE PK) presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
    • 08 Dec 2015 Results of population pharmacokinetics presented at the 57th Annual Meeting and Exposition of the American Society of Hematology
    • 14 Jun 2015 Results presented at the 20th Congress of the European Haematology Association.

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