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Phase 1 Safety and Tolerability Study of Human Monoclonal Antibody 5B1 (MVT-5873) With Expansion in Subjects With Pancreatic Cancer or Other CA19-9 Positive Malignancies

Trial Profile

Phase 1 Safety and Tolerability Study of Human Monoclonal Antibody 5B1 (MVT-5873) With Expansion in Subjects With Pancreatic Cancer or Other CA19-9 Positive Malignancies

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 09 Feb 2025

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At a glance

  • Drugs MVT 5873 (Primary) ; Gemcitabine; Paclitaxel
  • Indications Adenocarcinoma; Colon cancer; Lung cancer; Pancreatic cancer; Pancreatic ductal carcinoma
  • Focus Adverse reactions
  • Sponsors BioNTech; MabVax Therapeutics

Most Recent Events

  • 28 Jan 2025 Status changed from active, no longer recruiting to discontinued, as per Sponsor's decision.
  • 02 Sep 2024 Status changed from recruiting to active, no longer recruiting.
  • 22 Feb 2024 Planned End Date changed from 1 Feb 2024 to 1 Oct 2026.

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