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A Phase 1 Dose Escalation Study of LEE011 in Combination With Buparlisib and Letrozole for the Treatment of HR+, HER2-negative Post-menopausal Women With Locally Advanced or Metastatic Breast Cancer

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A Phase 1 Dose Escalation Study of LEE011 in Combination With Buparlisib and Letrozole for the Treatment of HR+, HER2-negative Post-menopausal Women With Locally Advanced or Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Ribociclib (Primary) ; Buparlisib; Letrozole
  • Indications Advanced breast cancer; HER2 negative breast cancer
  • Focus Adverse reactions
  • Acronyms LeeBLet
  • Sponsors Novartis Pharmaceuticals

    • Most Recent Events

    • 10 Jul 2017 Status changed from active, no longer recruiting to completed.
    • 11 Jul 2016 Planned End Date changed from 1 Jun 2016 to 1 Jul 2017.
    • 11 Jul 2016 Planned primary completion date changed from 1 Jun 2016 to 1 Jul 2017.

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