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A Phase I, Open-label, Non-randomised Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of a Single Oral Dose of AZD9291 in Patients With EGFRm Positive NSCLC Whose Disease Has Progressed on an EGFR TKI

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A Phase I, Open-label, Non-randomised Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of a Single Oral Dose of AZD9291 in Patients With EGFRm Positive NSCLC Whose Disease Has Progressed on an EGFR TKI

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jun 2023

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At a glance

  • Drugs Osimertinib (Primary) ; Itraconazole
  • Indications Non-small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 04 Jun 2023 Status changed from active, no longer recruiting to completed.
    • 13 Jan 2023 Planned End Date changed from 30 Dec 2022 to 29 Dec 2023.
    • 19 Jan 2022 Planned End Date changed from 31 Dec 2021 to 30 Dec 2022.

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