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An Open Label Phase II Trial of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) and Progeroid Laminopathies

Trial Profile

An Open Label Phase II Trial of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) and Progeroid Laminopathies

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2023

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At a glance

  • Drugs Lonafarnib (Primary) ; Pravastatin (Primary) ; Zoledronic acid (Primary)
  • Indications Progeria
  • Focus Therapeutic Use
  • Acronyms ProLon2

Most Recent Events

  • 23 Feb 2023 Planned End Date changed from 1 Dec 2022 to 1 Dec 2023.
  • 11 Jun 2021 Planned End Date changed from 1 Jul 2020 to 1 Dec 2022.
  • 11 Jun 2021 Planned primary completion date changed from 1 Jul 2020 to 1 Dec 2021.

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