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A Phase III, Open label, Randomised, Multi-centre, International Study of MEDI4736, versus Standard of Care in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (Stage IIIB-IV) Who Have Received at Least Two Prior Systemic Treatment Regimens Including One Platinum-based Chemotherapy Regimen and Do Not Have Known EGFR TK Activating Mutations or ALK Rearrangements (ARCTIC)

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Trial Profile

A Phase III, Open label, Randomised, Multi-centre, International Study of MEDI4736, versus Standard of Care in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (Stage IIIB-IV) Who Have Received at Least Two Prior Systemic Treatment Regimens Including One Platinum-based Chemotherapy Regimen and Do Not Have Known EGFR TK Activating Mutations or ALK Rearrangements (ARCTIC)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Jul 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary) ; Erlotinib; Gemcitabine; Vinorelbine
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ARCTIC
  • Sponsors AstraZeneca

    • Most Recent Events

    • 03 Oct 2023 Status changed from active, no longer recruiting to completed.
    • 19 Dec 2022 This trial has been completed in Italy, according to European Clinical Trials Database record.
    • 04 Nov 2022 According to European Clinical Trials Database record, this trial has been completed in Germany .

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