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The LOGIC 2 Trial A Phase II, Multi-center, Open-label Study of Sequential LGX818/MEK162 Combination Followed by a Rational Combination With Targeted Agents After Progression, to Overcome Resistance in Adult Patients With Locally Advanced or Metastatic BRAF V600 Melanoma

Trial Profile

The LOGIC 2 Trial A Phase II, Multi-center, Open-label Study of Sequential LGX818/MEK162 Combination Followed by a Rational Combination With Targeted Agents After Progression, to Overcome Resistance in Adult Patients With Locally Advanced or Metastatic BRAF V600 Melanoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Mar 2024

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At a glance

  • Drugs Binimetinib (Primary) ; Buparlisib (Primary) ; Capmatinib (Primary) ; Encorafenib (Primary) ; Infigratinib (Primary) ; Ribociclib (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms LOGIC-2
  • Sponsors Array BioPharma; Novartis; Pfizer
  • Most Recent Events

    • 05 Feb 2023 Status changed from active, no longer recruiting to completed.
    • 04 Dec 2022 Planned End Date changed from 31 Oct 2022 to 6 Jan 2023.
    • 04 Dec 2022 Planned primary completion date changed from 31 Oct 2022 to 6 Jan 2023.

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