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A Prospective Randomised, Open Label, Blinded Endpoint (PROBE) Study to Evaluate DUAL Antithrombotic Therapy With Dabigatran Etexilate (110mg and 150mg b.i.d.) Plus Clopidogrel or Ticagrelor vs. Triple Therapy Strategy With Warfarin (INR 2.0 - 3.0) Plus Clopidogrel or Ticagrelor and Aspirin in Patients With Non Valvular Atrial Fibrillation (NVAF) That Have Undergone a Percutaneous Coronary Intervention (PCI) With Stenting

Trial Profile

A Prospective Randomised, Open Label, Blinded Endpoint (PROBE) Study to Evaluate DUAL Antithrombotic Therapy With Dabigatran Etexilate (110mg and 150mg b.i.d.) Plus Clopidogrel or Ticagrelor vs. Triple Therapy Strategy With Warfarin (INR 2.0 - 3.0) Plus Clopidogrel or Ticagrelor and Aspirin in Patients With Non Valvular Atrial Fibrillation (NVAF) That Have Undergone a Percutaneous Coronary Intervention (PCI) With Stenting

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Jul 2019

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At a glance

  • Drugs Clopidogrel (Primary) ; Dabigatran etexilate (Primary) ; Ticagrelor (Primary) ; Aspirin; Warfarin
  • Indications Embolism
  • Focus Adverse reactions; Registrational
  • Acronyms RE-DUAL PCI
  • Sponsors Boehringer Ingelheim
  • Most Recent Events

    • 26 May 2019 Trial has been completed in Croatia and UK according to European Clinical Trials Database record.
    • 01 Mar 2019 Results of an ancillary analysis from the RE-DUAL PCI trial published in the American Heart Journal
    • 12 Feb 2019 Results of a sub-group analysis assessing Dabigatran dual therapy with ticagrelor or clopidogrel after percutaneous coronary intervention in atrial fibrillation patients with or without acute coronary syndrome, published in the European Heart Journal
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