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A Phase III, Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Assess the Efficacy and Safety of Tocilizumab in Subjects With Giant Cell Arteritis

Trial Profile

A Phase III, Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Assess the Efficacy and Safety of Tocilizumab in Subjects With Giant Cell Arteritis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 30 Jan 2023

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At a glance

  • Drugs Tocilizumab (Primary) ; Corticosteroids; Methotrexate; Prednisone
  • Indications Giant cell arteritis
  • Focus Registrational; Therapeutic Use
  • Acronyms GiACTA
  • Sponsors Genentech; Roche
  • Most Recent Events

    • 16 Nov 2022 Results evaluating longitudinal effects of both glucocorticoids (GCs) and tocilizumab, on hemoglobin A1c (HbA1c) during GC tapering, published in the Arthritis and Rheumatology
    • 14 Nov 2022 Results of post-hoc analysis assessing glucocorticoid toxicity in the treatment of giant cell arteritis, presented at the ACR Convergence 2022.
    • 01 Dec 2021 Results published in the American Journal of Respiratory and Critical Care Medicine.
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