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A Multi-center, Open-label Study to Assess the Long-term Safety of Droxidopa in Subjects With Primary Autonomic Failure, Dopamine Beta Hydroxylase Deficiency or Non-Diabetic Neuropathy and Symptomatic Neurogenic Orthostatic Hypotension

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Trial Profile

A Multi-center, Open-label Study to Assess the Long-term Safety of Droxidopa in Subjects With Primary Autonomic Failure, Dopamine Beta Hydroxylase Deficiency or Non-Diabetic Neuropathy and Symptomatic Neurogenic Orthostatic Hypotension

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 May 2019

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At a glance

  • Drugs Droxidopa (Primary)
  • Indications Orthostatic hypotension
  • Focus Adverse reactions
  • Sponsors Chelsea Therapeutics

    • Most Recent Events

    • 06 Jan 2017 Results (n=907) assessing CV safety of Droxidopa using patient data from NOH-301, NOH-302, NOH-303, NOH-304 and NOH-306 trials published in the American Journal of Cardiology.
    • 21 Apr 2016 Results of an integrated analysis from five trials assessing cardiovascular safety presented at the 68th Annual Meeting of the American Academy of Neurology
    • 18 Jun 2015 Pooled cardiovascular safety analysis, results presented at the 19th International Congress of Parkinson's Disease and Movement Disorders.

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