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A 16-Week, International, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Oral UT-15C Sustained Release Tablets in Subjects With Pulmonary Arterial Hypertension

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Trial Profile

A 16-Week, International, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Oral UT-15C Sustained Release Tablets in Subjects With Pulmonary Arterial Hypertension

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Feb 2023

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At a glance

  • Drugs Treprostinil (Primary)
  • Indications Pulmonary arterial hypertension
  • Focus Registrational; Therapeutic Use
  • Acronyms FREEDOM-C2
  • Sponsors United Therapeutics Corporation

    • Most Recent Events

    • 29 Aug 2022 Results of post-hoc analysis (FREEDOM-C and FREEDOM-C2) assessing efficacy and dose-response relationship of oral treprostinil in pulmonary arterial hypertension patients on monotherapy or dual background therapy, presented at the ESC Congress 2022 - Annual Congress of the European Society of Cardiology.
    • 24 May 2017 Results of secondary analysis (n=178) from this trial assessing correlation between increased endothelial activation with mitochondrial dysfunction in patients with pulmonary arterial hypertension, presented at the 113th International Conference of the American Thoracic Society.
    • 24 May 2017 Results of secondary analysis from FREEDOM-C2 trial presented at the 113th International Conference of the American Thoracic Society

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