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The effects of tolvaptan on renal handling of water and sodium, vasoactive hormones and circulatory system, during basal conditions and during inhibition of the nitric oxide system in healthy subjects. A dose-response study.

Trial Profile

The effects of tolvaptan on renal handling of water and sodium, vasoactive hormones and circulatory system, during basal conditions and during inhibition of the nitric oxide system in healthy subjects. A dose-response study.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Mar 2017

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At a glance

  • Drugs Tolvaptan (Primary)
  • Indications Hyponatraemia; Kidney disorders
  • Focus Pharmacodynamics
  • Acronyms DOVA
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 20 Dec 2014 Status changed from active, no longer recruiting to completed as reported by EU Clinical Trials Register record.
    • 08 Oct 2014 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
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