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PROBE TRIAL (Pilot Rilpivirine Observational Evaluation) Monocenter, national, prospective, open label, pilot, proof-of-concept study on the use of rilpivirine as substitutive agent for the HAART nucleosidic backbone in virologic suppressed patients.

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Trial Profile

PROBE TRIAL (Pilot Rilpivirine Observational Evaluation) Monocenter, national, prospective, open label, pilot, proof-of-concept study on the use of rilpivirine as substitutive agent for the HAART nucleosidic backbone in virologic suppressed patients.

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 03 Mar 2016

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At a glance

  • Drugs Rilpivirine (Primary) ; Darunavir; Ritonavir
  • Indications HIV-1 infections
  • Focus Proof of concept; Registrational; Therapeutic Use
  • Acronyms PROBE

Most Recent Events

  • 20 Feb 2016 Primary endpoint has been met, (Non-inferiority of the virological response between treatment groups according to FDA snapshot approach, at 24 and 48 weeks), according to results published.
  • 20 Feb 2016 Results published in the JAIDS.
  • 24 Oct 2015 Status changed from recruiting to active, no longer recruiting, according to results published.

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