Trial Profile
Double-blind, Randomized, Placebo-controlled, Single Site Study to Evaluate the Effects of Evolocumab (AMG 145) Treatment, Alone and in Combination With Atorvastatin, on Lipoprotein Kinetics
Status:
Completed
Phase of Trial:
Phase III
Latest Information Update: 06 Nov 2021
Price :
$35
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At a glance
- Drugs Atorvastatin (Primary) ; Evolocumab (Primary)
- Indications Dyslipidaemias; Hyperlipidaemia
- Focus Registrational; Therapeutic Use
- Acronyms FLOREY; PROFICIO
- Sponsors Amgen
- 16 Mar 2018 Results (n=63) assessing the effects of evolocumab against PCSK9 and lowers Lp (a) in subjects with baseline plasma apo (a) concentrations greater than 5nmol per L along with substudy results, published in the European Heart Journal.
- 30 Aug 2017 Results assessing factorial effects of Evolocumab and Atorvastatin on lipoprotein metabolism, were presented at the ESC Congress 2017: Annual Congress of the European Society of Cardiology.
- 21 Aug 2017 According to an Amgen media release, data feom this trial will be presented at the European Society of Cardiology (ESC) Congress 2017.