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A Phase IB Study of the Combination of AZD6244 Hydrogen Sulfate (Selumetinib) and Cyclosporin A (CsA) in Patients With Advanced Solid Tumors With an Expansion Cohort in Metastatic Colorectal Cancer

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A Phase IB Study of the Combination of AZD6244 Hydrogen Sulfate (Selumetinib) and Cyclosporin A (CsA) in Patients With Advanced Solid Tumors With an Expansion Cohort in Metastatic Colorectal Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Feb 2025

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At a glance

  • Drugs Selumetinib (Primary) ; Ciclosporin
  • Indications Cervical cancer; Colorectal cancer; Endometrial cancer; Liver cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 11 Feb 2025 Status changed from active, no longer recruiting to completed.
    • 20 Mar 2024 Planned End Date changed from 7 Mar 2024 to 19 Mar 2025.
    • 24 Jul 2018 Results published in the Cancer Research

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