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A Phase I/IIb Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given With Adjuvant Poly-ICLC in Combination With INCB024360 for Patients in Remission With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma Whose Tumors Express NY-ESO-1 or LAGE-1 Antigen

Trial Profile

A Phase I/IIb Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given With Adjuvant Poly-ICLC in Combination With INCB024360 for Patients in Remission With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma Whose Tumors Express NY-ESO-1 or LAGE-1 Antigen

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 Oct 2019

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At a glance

  • Drugs Epacadostat (Primary) ; Poly ICLC; Rasdegafusp-alfa
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 15 Mar 2019 Planned End Date changed from 12 Feb 2021 to 12 Feb 2023.
    • 15 Mar 2019 Planned primary completion date changed from 12 Feb 2020 to 12 Feb 2022.
    • 31 Aug 2018 Biomarkers information updated
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