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A Phase I/IIb Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given With Adjuvant Poly-ICLC in Combination With INCB024360 for Patients in Remission With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma Whose Tumors Express NY-ESO-1 or LAGE-1 Antigen

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Trial Profile

A Phase I/IIb Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given With Adjuvant Poly-ICLC in Combination With INCB024360 for Patients in Remission With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma Whose Tumors Express NY-ESO-1 or LAGE-1 Antigen

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 28 Feb 2023

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At a glance

  • Drugs Epacadostat (Primary) ; Poly ICLC; Rasdegafusp-alfa
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 27 Jan 2023 Primary efficacy and safety endpoint measures amended.
  • 20 Jul 2021 Status changed from active, no longer recruiting to completed.
  • 30 Apr 2021 Planned End Date changed from 27 Mar 2022 to 20 Aug 2021.

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