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Prospective Randomized Trial of an Adjuvant Therapy of Completely Resected Merkel Cell Carcinoma (MCC) With Immune Checkpoint Blocking Antibodies (Nivolumab, Opdivo; Ipilimumab (Yervoy) Every 3 Weeks for 12 Weeks Versus Observation

Trial Profile

Prospective Randomized Trial of an Adjuvant Therapy of Completely Resected Merkel Cell Carcinoma (MCC) With Immune Checkpoint Blocking Antibodies (Nivolumab, Opdivo; Ipilimumab (Yervoy) Every 3 Weeks for 12 Weeks Versus Observation

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Apr 2025

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
  • Indications Merkel cell carcinoma
  • Focus Therapeutic Use
  • Acronyms ADMEC; ADMEC- O; DeCOG/ADO study

Most Recent Events

  • 09 Apr 2025 Status changed from active, no longer recruiting to completed.
  • 13 Sep 2022 Results presented at the 47th European Society for Medical Oncology Congress
  • 13 Sep 2022 Planned End Date changed from 31 Aug 2022 to 31 Aug 2024.

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