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A Phase 3, Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Guselkumab for the Treatment of Subjects With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab

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Trial Profile

A Phase 3, Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Guselkumab for the Treatment of Subjects With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Apr 2023

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At a glance

  • Drugs Guselkumab (Primary) ; Ustekinumab
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms NAVIGATE
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 06 Apr 2023 Results of pooled analysis from Phase 2/3 studies (X-PLORE, VOYAGE 1, VOYAGE 2, NAVIGATE, ORION, ECLIPSE, Japan registration) assessing guselkumab safety in patients with psoriasispublished in the British Journal of Dermatology
  • 21 Mar 2023 Results of post-hoc analysis evaluating the subgroup of patients with residual psoriasis of mild severity , presented at the American Academy of Dermatology annual Meeting 2023
  • 06 Nov 2019 Results presented at the 22nd Annual European Congress of the International Society for Pharmacoeconomics and Outcomes Research

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