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A Phase 4 Safety And Efficacy Study Of Bosutinib (Bosulif (Registered)) In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase Inhibitors

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Trial Profile

A Phase 4 Safety And Efficacy Study Of Bosutinib (Bosulif (Registered)) In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase Inhibitors

Status: Discontinued
Phase of Trial: Phase IV

Latest Information Update: 04 Aug 2023

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At a glance

  • Drugs Bosutinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms BYOND
  • Sponsors Pfizer

    • Most Recent Events

    • 15 Jun 2023 Results of post-hoc pooled analysis of B1871006 (NCT00261846), B1871007 (NCT00811070), B1871039 (NCT02228382, BYOND) B1871048 (NCT03128411), B1871008 (NCT00574873) & (B1871040, NCT01903733) assessing effect of BMI on the safety of bosutinib in patients with previously treated or newly diagnosed CML, presented at the 28th Congress of the European Haematology Association.
    • 17 Jun 2022 Results of sub-analysis (n=48) assessing efficacy and safety of bosutinib in resistant and intolerant patients with CML, presented at the 27th Congress of the European Haematology Association
    • 07 Jun 2022 Results of sub-analysis of 48 patients treated with 2 (3L) and 3 (4L) prior TKIs categorized by resistance/intolerance to the last received TKI, presented at the 58th Annual Meeting of the American Society of Clinical Oncology.
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