Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A randomised trial of dolutegravir (DTG)-based antiretroviral therapy vs standard of care (SOC) in children with HIV infection starting first-line or switching to second-line ART

Trial Profile

A randomised trial of dolutegravir (DTG)-based antiretroviral therapy vs standard of care (SOC) in children with HIV infection starting first-line or switching to second-line ART

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 25 Apr 2024

Price :
$35 *
Note:
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Abacavir/dolutegravir/lamivudine (Primary) ; Dolutegravir (Primary) ; Antiretrovirals; Atazanavir; Efavirenz; Lamivudine/abacavir; Lamivudine/zidovudine; Lopinavir; Lopinavir/ritonavir; Nevirapine; Raltegravir
  • Indications HIV-1 infections
  • Focus Registrational; Therapeutic Use
  • Acronyms ODYSSEY; ODYSSEY A; ODYSSEY B

Most Recent Events

  • 06 Mar 2024 Results (n=683) assessing the efficacy and safety of DTG versus SOC during extended follow-up at a time-point of 192 weeks in Africa and Thailand, presented at the 31st Conference on Retroviruses and Opportunistic Infections 2024
  • 05 Sep 2023 According to Viatris Inc. media release, the company announced U.S. Food and Drug Administration (FDA) tentative approval for a New Drug Application for abacavir 60 mg/dolutegravir 5 mg/lamivudine 30 mg tablets for oral suspension for the treatment of HIV-1 infection in paediatric patients.
  • 22 Feb 2023 Results of PopPK model developed using data from IMPAACT P1093 and PENTA ODYSSEY; evaluating DTG BID dosing in 1st generation INSTI-r (raltegravir or elvitegravir) and extrapolating efficacy and safety from adults to pediatric population, presented at the 30th Conference on Retroviruses and Opportunistic Infections 2023

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top