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A Phase I/II Study of the Selective Inhibitor of Nuclear Export Selinexor (KPT-330) in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

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Trial Profile

A Phase I/II Study of the Selective Inhibitor of Nuclear Export Selinexor (KPT-330) in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Selinexor (Primary) ; Cytarabine; Fludarabine; Hydrocortisone; Methotrexate
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions
  • Acronyms SELHEM

    • Most Recent Events

    • 01 Mar 2017 Status changed from recruiting to completed.
    • 22 Feb 2017 Planned number of patients changed from 45 to 62.
    • 02 Nov 2016 Planned End Date changed from 1 Oct 2016 to 1 Sep 2018.

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