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A Phase III, Double-masked, Multicenter, Randomized, Active Treatment-controlled Study of the Efficacy and Safety of 0.5 mg and 2.0 mg Ranibizumab Administered Monthly or on an As-needed Basis (PRN) in Patients With Sub-foveal Neovascular Age-related Macular Degeneration

Trial Profile

A Phase III, Double-masked, Multicenter, Randomized, Active Treatment-controlled Study of the Efficacy and Safety of 0.5 mg and 2.0 mg Ranibizumab Administered Monthly or on an As-needed Basis (PRN) in Patients With Sub-foveal Neovascular Age-related Macular Degeneration

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Oct 2024

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At a glance

  • Drugs Ranibizumab (Primary)
  • Indications Choroidal neovascularisation; Wet age-related macular degeneration
  • Focus Registrational; Therapeutic Use
  • Acronyms HARBOR
  • Sponsors Genentech
  • Most Recent Events

    • 01 Oct 2024 Results published in the Retina
    • 01 Apr 2023 Results of post-hoc analysis assessing subretinal fluid (SRF) and/or intraretinal fluid recurrence in patients with neovascular age-related macular degeneration who received as-needed ranibizumab, published in the Retina.
    • 28 Nov 2022 Results of post hoc analysis(n=917) assessing Relationship between retinal fluid characteristics and vision in neovascular age-related macular degeneration published in the Graefes Archive for Clinical and Experimental Ophthalmology

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