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A Randomised, Double-blind, Placebo-controlled, Dose Escalation Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics of Different Doses (0.2, 0.6, 2.0, 6.0, and 20.0 μg/hr) of BIWH 3 Administered for 6 Hours in Patients With Chronic Critical Limb Ischaemia (CLI, Fontaine Class III or IV).

Trial Profile

A Randomised, Double-blind, Placebo-controlled, Dose Escalation Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics of Different Doses (0.2, 0.6, 2.0, 6.0, and 20.0 μg/hr) of BIWH 3 Administered for 6 Hours in Patients With Chronic Critical Limb Ischaemia (CLI, Fontaine Class III or IV).

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 21 Oct 2014

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At a glance

  • Drugs BIWH 3 (Primary)
  • Indications Ischaemia; Peripheral arterial occlusive disorders
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms COINART-1
  • Sponsors Boehringer Ingelheim
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 21 Aug 2014 New trial record
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