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A Phase 1 Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors

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A Phase 1 Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 May 2019

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At a glance

  • Drugs Efizonerimod-alfa (Primary) ; Durvalumab
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors MedImmune

Most Recent Events

  • 12 Mar 2019 Status changed from active, no longer recruiting to completed.
  • 20 Jun 2016 Planned number of patients changed from 224 to 39.
  • 20 Jun 2016 Status changed from recruiting to active, no longer recruiting.

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