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A Phase I Study Combining Ibrutinib With Rituximab, Ifosfamide, Carboplatin, and Etoposide (R-ICE) in Patients With Relapsed or Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

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Trial Profile

A Phase I Study Combining Ibrutinib With Rituximab, Ifosfamide, Carboplatin, and Etoposide (R-ICE) in Patients With Relapsed or Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Ibrutinib (Primary) ; Carboplatin; Etoposide; Ifosfamide; Rituximab
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions

    • Most Recent Events

    • 31 Jan 2018 Results (n=21) assessing efficacy and safety of ibrutinib in combination with standard R-ICE for patients with rel/ref DLBCL, were published in the Blood.
    • 24 Jan 2018 Status changed from active, no longer recruiting to completed.
    • 12 Jul 2017 Status changed from recruiting to active, no longer recruiting.

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