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A Phase 1/2, Open-Label Study to Assess the Safety and Tolerability of Repeat Doses of Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects Following Cyclophosphamide Conditioning

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Trial Profile

A Phase 1/2, Open-Label Study to Assess the Safety and Tolerability of Repeat Doses of Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects Following Cyclophosphamide Conditioning

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs SB 728 T (Primary) ; Cyclophosphamide
  • Indications HIV infections
  • Focus Adverse reactions
  • Sponsors Sangamo Therapeutics

Most Recent Events

  • 01 Jul 2019 Status changed from active, no longer recruiting to completed.
  • 06 Jan 2017 According to a Sangamo Therapeutics media release, this trial was originally conducted by Sangamo BioSciences but later on this company's name changed to Sangamo Therapeutics.
  • 06 Jan 2017 Planned primary completion date changed from 1 Mar 2018 to 1 Jun 2018.

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