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A Multi-center, Phase 2 Study Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC in Combination With tPA, Mechanical Thrombectomy or Both in Moderate to Severe Acute Ischemic Stroke

Trial Profile

A Multi-center, Phase 2 Study Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC in Combination With tPA, Mechanical Thrombectomy or Both in Moderate to Severe Acute Ischemic Stroke

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Feb 2020

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At a glance

  • Drugs 3K3A APC (Primary)
  • Indications Stroke
  • Focus Adverse reactions
  • Acronyms RHAPSODY
  • Sponsors ZZ Biotech
  • Most Recent Events

    • 21 Feb 2020 Results Characterizing Cerebral Morphometry Changes and Effects of 3K3A-APC in Ischemic Stroke, presented at the International Stroke Conference 2020
    • 21 Feb 2020 Results of hemorrhagic transformation when co-administered with conventional recanalization in acute ischemic stroke patients were presented at the International Stroke Conference 2020
    • 18 Nov 2018 Results determining the maximally tolerated dose (MTD), published in the Annals of Neurology.
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