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A Multi-Center, Two-Stage, Open-Label Phase I and Randomized, Active Controlled, Masked Phase II Study to Evaluate the Safety and Efficacy of Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology Compared With Eylea for the Treatment of Recurrent CNV Secondary to AMD

Trial Profile

A Multi-Center, Two-Stage, Open-Label Phase I and Randomized, Active Controlled, Masked Phase II Study to Evaluate the Safety and Efficacy of Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology Compared With Eylea for the Treatment of Recurrent CNV Secondary to AMD

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 17 Nov 2016

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At a glance

  • Drugs NT 503 (Primary) ; Aflibercept
  • Indications Age-related macular degeneration; Choroidal neovascularisation
  • Focus Therapeutic Use
  • Sponsors GNT Pharma
  • Most Recent Events

    • 08 Jan 2016 Planned number of patients changed from 170 to 110 as per ClinicalTrials.gov record.
    • 08 Jan 2016 Planned End Date changed from 1 Mar 2018 to 1 Aug 2018 as per ClinicalTrials.gov record.
    • 08 Jan 2016 Planned primary completion date changed from 1 Dec 2017 to 1 Apr 2018 as per ClinicalTrials.gov record.
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