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A Multicenter, Open-Label, Randomized, Dose-Finding Study Testing the Safety, Tolerability, and Pharmacokinetics (PK) of ND0612, a Liquid Formulation of Levodopa/Carbidopa (LD/CD) Delivered as a Continuous Subcutaneous Infusion (SC) in Parkinson's Disease (PD) Patients Treated With LD

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A Multicenter, Open-Label, Randomized, Dose-Finding Study Testing the Safety, Tolerability, and Pharmacokinetics (PK) of ND0612, a Liquid Formulation of Levodopa/Carbidopa (LD/CD) Delivered as a Continuous Subcutaneous Infusion (SC) in Parkinson's Disease (PD) Patients Treated With LD

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 May 2024

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At a glance

  • Drugs Levodopa/carbidopa (Primary) ; Carbidopa; Entacapone; Levodopa
  • Indications Parkinson's disease
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors NeuroDerm

    • Most Recent Events

    • 04 Dec 2019 Status changed from recruiting to completed.
    • 08 Jun 2017 Pooled (n=46) results of NCT02096601 and NCT01883505 trials assessing levodopa pharmacokinetic profile derived from continuous subcutaneous (SC) administration of ND0612, presented at the 21st International Congress of Parkinson's Disease and Movement Disorders
    • 28 Apr 2017 Results assessing levodopa pharmacokinetic profile after continuous subcutaneous administration of ND0612, presented at the 69th Annual Meeting of the American Academy of Neurology

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