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A Pilot Study to Evaluate the Feasibility, Safety and Engraftment of Zinc Finger Nuclease (ZFN) CCR5 Modified CD34+ Hematopoietic Stem/Progenitor Cells (SB-728mR-HSPC) in HIV-1 (R5) Infected Patients

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Trial Profile

A Pilot Study to Evaluate the Feasibility, Safety and Engraftment of Zinc Finger Nuclease (ZFN) CCR5 Modified CD34+ Hematopoietic Stem/Progenitor Cells (SB-728mR-HSPC) in HIV-1 (R5) Infected Patients

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Jul 2025

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At a glance

  • Drugs SB 728 HSC (Primary) ; Busulfan
  • Indications HIV-1 infections
  • Focus Adverse reactions

Most Recent Events

  • 04 Jul 2025 Planned End Date changed from 13 Jun 2025 to 26 Aug 2025.
  • 04 Jul 2025 Planned primary completion date changed from 10 Dec 2021 to 26 Aug 2025.
  • 03 Jan 2025 Planned End Date changed from 13 Dec 2024 to 13 Jun 2025.

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