A Phase Ib/II Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer

Trial Profile

A Phase Ib/II Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 05 Jun 2018

At a glance

  • Drugs Neratinib (Primary) ; Trastuzumab emtansine
  • Indications Adenocarcinoma; Advanced breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 05 Jun 2018 Results of phase Ib dose-escalstion part of this study presented at the 54th Annual Meeting of the American Society of Clinical Oncology.
    • 02 Jun 2018 Results published in the Puma Biotechnology Media Release
    • 01 Mar 2018 According to a Puma Biotechnology media release, the company expects to report updated data from this trial in the second quarter of 2018.
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