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A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of Orally Administered CB-5083 in Subjects With Advanced Solid Tumors

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Trial Profile

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of Orally Administered CB-5083 in Subjects With Advanced Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs CB 5083 (Primary)
  • Indications Primitive neuroectodermal tumours; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Cleave Therapeutics

    • Most Recent Events

    • 27 Feb 2018 Status changed from active, no longer recruiting to discontinued.
    • 15 Jun 2017 Status changed from recruiting to active, no longer recruiting.
    • 21 Apr 2016 Planned number of patients changed from 75 to 150.

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