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A Phase 2a Study of ALXN1007 in Subjects With Newly Diagnosed Acute Graft-versus-Host Disease Involving the Lower Gastrointestinal Tract

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Trial Profile

A Phase 2a Study of ALXN1007 in Subjects With Newly Diagnosed Acute Graft-versus-Host Disease Involving the Lower Gastrointestinal Tract

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2023

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At a glance

  • Drugs Olendalizumab (Primary)
  • Indications Graft-versus-host disease
  • Focus Proof of concept; Therapeutic Use
  • Acronyms GIGVHD
  • Sponsors Alexion AstraZeneca Rare Disease
  • Most Recent Events

    • 18 May 2023 Results assessing the safety and efficacy of ALXN1007 in patients with newly diagnosed LGI acute GVHD receiving concomitant corticosteroid published in the Bone Marrow Transplantation
    • 15 Mar 2017 Status changed from active, no longer recruiting to discontinued.
    • 27 Feb 2017 Planned primary completion date changed from 1 Jun 2017 to 1 Feb 2017.

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