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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Nonsteroidal Aromatase Inhibitors (Anastrozole or Letrozole) Plus LY2835219, a CDK4/6 Inhibitor, or Placebo in Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative Locoregionally Recurrent or Metastatic Breast Cancer With No Prior Systemic Therapy in This Disease Setting

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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Nonsteroidal Aromatase Inhibitors (Anastrozole or Letrozole) Plus LY2835219, a CDK4/6 Inhibitor, or Placebo in Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative Locoregionally Recurrent or Metastatic Breast Cancer With No Prior Systemic Therapy in This Disease Setting

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Oct 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; Anastrozole; Letrozole
  • Indications Advanced breast cancer; HER2 negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms MONARCH 3
  • Sponsors Eli Lilly and Company; Eli Lilly Japan

    • Most Recent Events

    • 07 Oct 2024 Planned End Date changed from 16 Dec 2024 to 1 Dec 2025.
    • 25 Jul 2024 This study has been completed in Sweden.
    • 25 Apr 2024 This study has been completed in Belgium, according to European Clinical Trials Database record.

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