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The Effect of Multiple Doses of BI 187004 on the Single Dose Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P-glycoprotein Substrate (Digoxin) Administered Orally in an Open-label, One-sequence Trial in Healthy Subjects

Trial Profile

The Effect of Multiple Doses of BI 187004 on the Single Dose Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P-glycoprotein Substrate (Digoxin) Administered Orally in an Open-label, One-sequence Trial in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Sep 2016

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At a glance

  • Drugs BI 187004 CL (Primary) ; Caffeine; Digoxin; Metoprolol; Midazolam; Omeprazole; Warfarin
  • Indications Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Boehringer Ingelheim
  • Most Recent Events

    • 22 Dec 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 19 Nov 2014 Status changed from recruiting to active, no longer recruiting as per ClinicalTrials.gov.
    • 26 Oct 2014 Status changed from not yet recruiting to recruiting, as per ClinicalTrials.gov record.
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